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1

Role of Cell Death in Toxicology: Does It Matter How Cells Die?

Journal:

Annual Review of Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.84 MB

english, 2019

2

Mitochondria in cancer cells: what is so special about them?

Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky

Journal:

Trends in Cell Biology

Year:

2008

Language:

english

File:

PDF, 495 KB

english, 2008

3

Mitochondrial Oxidative Stress: Implications for Cell Death

Orrenius, Sten, Gogvadze, Vladimir, Zhivotovsky, Boris

Journal:

Annual Review of Pharmacology

Year:

2007

Language:

english

File:

PDF, 461 KB

english, 2007

4

Calcium-Mediated Mechanisms in Chemically Induced Cell Death

Nicotera, Pierluigi, Bellomo, Giorgio, Orrenius, Sten

Journal:

Annual Review of Pharmacology

Year:

1992

Language:

english

File:

PDF, 795 KB

english, 1992

5

Mitochondria, oxidative stress and cell death

Martin Ott, Vladimir Gogvadze, Sten Orrenius, Boris Zhivotovsky

Journal:

Year:

2007

Language:

english

File:

PDF, 325 KB

english, 2007

6

All along the watchtower: on the regulation of apoptosis regulators

FADEEL, BENGT, ZHIVOTOVSKY, BORIS, ORRENIUS, STEN

Journal:

The FASEB Journal

Year:

1999

Language:

english

File:

PDF, 264 KB

english, 1999

7

Autophagy in Toxicology: Cause or Consequence?

Orrenius, Sten, Kaminskyy, Vitaliy O., Zhivotovsky, Boris

Journal:

Annual Review of Pharmacology

Year:

2013

Language:

english

File:

PDF, 508 KB

english, 2013

8

Mechanism of allyl alcohol toxicity and protective effects of low-molecular-weight thiols studies with isolated rat hepatocytes

Yasuo Ohno, Kari Ormstad, David Ross, Sten Orrenius

Journal:

Toxicology and Applied Pharmacology

Year:

1985

Language:

english

File:

PDF, 872 KB

english, 1985

9

Mitochondria, oxygen metabolism and the regulation of cell death

Joya Chandra, Sten Orrenius

Journal:

International Congress Series

Year:

2002

Language:

english

File:

PDF, 165 KB

english, 2002

10

Calcium and mitochondria in the regulation of cell death

Orrenius, Sten, Gogvadze, Vladimir, Zhivotovsky, Boris

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 764 KB

english, 2015

11

Calcineurin and mitochondrial function in glutamate-induced neuronal cell death

Maria Ankarcrona, Jeannette M. Dypbukt, Sten Orrenius, Pierluigi Nicotera

Journal:

Year:

1996

Language:

english

File:

PDF, 368 KB

english, 1996

12

Interaction of menadione (2-methyl-1,4-naphthoquinone) with glutathione

David Ross, Hjordis Thor, Sten Orrenius, Peter Moldeus

Journal:

Chemico-Biological Interactions

Year:

1985

Language:

english

File:

PDF, 531 KB

english, 1985

13

HAMLET, protein folding, and tumor cell death

K. Hun Mok, Jenny Pettersson, Sten Orrenius, Catharina Svanborg

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 400 KB

english, 2007

14

Calcium and cell death mechanisms: A perspective from the cell death community

Boris Zhivotovsky, Sten Orrenius

Journal:

Year:

2011

Language:

english

File:

PDF, 841 KB

english, 2011

15

Proteases in Fas-mediated apoptosis

Boris Zhivotovsky, David H. Burgess, Jörg Schlegel, M. Isabella Pörn, Daina Vanags, Sten Orrenius

Journal:

Journal of Cellular Biochemistry

Year:

1997

Language:

english

File:

PDF, 156 KB

english, 1997

16

Cellular signalling in programmed cell death (apoptosis)

David J McConkey, Sten Orrenius, Mikael Jondal

Journal:

Immunology Today

Year:

1990

Language:

english

File:

PDF, 564 KB

english, 1990

17

A folding variant of human α-lactalbumin induces mitochondrial permeability transition in isolated mitochondria

Camilla Köhler, Vladimir Gogvadze, Anders Håkansson, Catharina Svanborg, Sten Orrenius, Boris Zhivotovsky

Journal:

Year:

2001

Language:

english

File:

PDF, 476 KB

english, 2001

18

Clinical perspectives of cell death: where we are and where to go…

Boris Zhivotovsky, Sten Orrenius

Journal:

Year:

2009

Language:

english

File:

PDF, 118 KB

english, 2009

19

Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity

Robertson, John D, Gogvadze, Vladimir, Kropotov, Andrey, Vakifahmetoglu, Helin, Zhivotovsky, Boris, Orrenius, Sten

Journal:

Year:

2004

Language:

english

File:

PDF, 204 KB

english, 2004

20

Protease Activation in Apoptosis Induced by MAL

Camilla Köhler, Anders Håkansson, Catharina Svanborg, Sten Orrenius, Boris Zhivotovsky

Journal:

Experimental Cell Research

Year:

1999

Language:

english

File:

PDF, 212 KB

english, 1999

21

Induction of dna damage by menadione (2-methyl-1,4-naphthoquinone) in primary cultures of rat hepatocytes

Helen Morrison, Bengt Jernström, Magnus Nordenskjöld, Hjördis Thor, Sten Orrenius

Journal:

Biochemical Pharmacology

Year:

1984

Language:

english

File:

PDF, 1.00 MB

english, 1984

22

Cyclosporin a protects hepatocytes against prooxidant-induced cell killing: A study on the role of mitochondrial Ca2+ cycling in cytotoxicity

George E.N. Kass, Marlene J. Juedes, Sten Orrenius

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.14 MB

english, 1992

23

Solubilization and partial purification of cytochrome P-450 from rat lung microsomes

Bengt Jernström, Jorge Capdevila, Sten Jakobsson, Sten Orrenius

Journal:

Biochemical and Biophysical Research Communications

Year:

1975

Language:

english

File:

PDF, 476 KB

english, 1975

24

Programmed to die: The mitochondria in the focus of apoptosis research : Britton Chance Honor Lecture

Journal:

Pathophysiology

Year:

1998

Language:

english

File:

PDF, 157 KB

english, 1998

25

Fatty acid inducible cytochrome P-454 of rat kidney cortex microsomes

Sten Jakobsson, Hjördis Thor, Sten Orrenius

Journal:

Biochemical and Biophysical Research Communications

Year:

1970

Language:

english

File:

PDF, 413 KB

english, 1970

26

Conversion of agroclavine by mammalian cytochrome P-450

Wilson, Beverley J., Ramstad, Egil, Jansson, Ingela, Orrenius, Sten

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1971

Language:

english

File:

PDF, 1.00 MB

english, 1971

27

Demonstration of Nuclear Compartmentalization of Glutathione in Hepatocytes

Giorgio Bellomo, Mariapia Vairetti, Lucianna Stivala, Francesca Mirabelli, Plinio Richelmi and Sten Orrenius

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.11 MB

english, 1992

28

Apoptosis and cancer: where we are and where to go …

Boris Zhivotovsky, Sten Orrenius

Journal:

Seminars in Cancer Biology

Year:

2003

Language:

english

File:

PDF, 32 KB

english, 2003

29

Stereospecificity of certain reduced nicotinamide-adenine dinucleotide phosphate-linked reactions in rat liver microsomes

Manik Das, Sten Orrenius, Lars Ernster, Yvonne Gnosspelius

Journal:

Year:

1968

Language:

english

File:

PDF, 312 KB

english, 1968

30

Hydroperoxide-supported cytochrome P-450-linked fatty acid hydroxylation in liver microsomes

A˚ke Ellin, Sten Orrenius

Journal:

Year:

1975

Language:

english

File:

PDF, 320 KB

english, 1975

31

On the relationship between Ca2+ efflux and membrane damage during t-butylhydroperoxide metabolism by liver mitochondria

Gregory A. Moore, Sarah A. Jewell, Giorgio Bellomo, Sten Orrenius

Journal:

Year:

1983

Language:

english

File:

PDF, 348 KB

english, 1983

32

Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis

Mark B Hampton, Sten Orrenius

Journal:

Year:

1997

Language:

english

File:

PDF, 561 KB

english, 1997

33

Cytochrome c release and caspase activation in hydrogen peroxide- and tributyltin-induced apoptosis

Hélène Stridh, Monica Kimland, Dean P. Jones, Sten Orrenius, Mark B. Hampton

Journal:

Year:

1998

Language:

english

File:

PDF, 309 KB

english, 1998

34

Signalling mechanisms and oxidative stress in apoptosis

Andrew F.G. Slater, C. Stefan, I. Nobel, Diels J. Van Den Dobbelsteen, sten Orrenius

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 495 KB

english, 1995

35

Phenobarbital-induced synthesis of the oxidative demethylating enzymes of rat liver microsomes

Sten Orrenius, Lars Ernster

Journal:

Biochemical and Biophysical Research Communications

Year:

1964

Language:

english

File:

PDF, 255 KB

english, 1964

36

ENHANCEMENT OF GLUCURONYLATING ENZYMES AND MITOCHONDRIAL OXIDATIVE ENZYMES IN LIVERS OF RATS TREATED WITH PHENOBARBITAL*

Zeidenberg, Phillip, Orrenius, Sten, Ernster, Lars

Journal:

Transactions of the New York Academy of Sciences

Year:

1967

Language:

english

File:

PDF, 328 KB

english, 1967

37

Mitochondrial cytochrome c release may occur by volume-dependent mechanisms not involving permeability transition

GOGVADZE, Vladimir, ROBERTSON, John D., ENOKSSON, Mari, ZHIVOTOVSKY, Boris, ORRENIUS, Sten

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 176 KB

english, 2004

38

REDOX MODULATION OF APOPTOTIC CELL DEATH

Orrenius, Sten, Nobel, Stefan

Journal:

Biochemical Society Transactions

Year:

1996

Language:

english

File:

PDF, 120 KB

english, 1996

39

1,10-Phenanthroline stimulates internucleosomal DNA fragmentation in isolated rat-liver nuclei by promoting the redox activity of endogenous copper ions

BURKITT, Mark J., MILNE, Lesley, NICOTERA, Pierluigi, ORRENIUS, Sten

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 485 KB

english, 1996

40

Alterations in Bcl-2/Bax protein levels in platelets form part of an ionomycin-induced process that resembles apoptosis

Daina M Vanags, Sten Orrenius, Miguel Aguilar-Santelises

Journal:

British Journal of Haematology

Year:

1997

Language:

english

File:

PDF, 614 KB

english, 1997

41

Signal Transduction Pathways in Apoptosis

Dr. David J. McConkey, Sten Orrenius

Journal:

Year:

1996

Language:

english

File:

PDF, 63 KB

english, 1996

42

Metabolic regulation in oxidative stress

Sten Orrenius, Georges E.N. Kass, Pierluigi Nicotera

Journal:

Free Radical Biology and Medicine

Year:

1990

Language:

english

File:

PDF, 113 KB

english, 1990

43

Cytochrome P-450-product Complexes Produced by Amphetamine Derivatives: A Comparative Study with Isolated Liver Microsomes and Hepatocytes

Masaharu Hirata, Johan Högberg, Hjördis Thor, Sten Orrenius

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1977

Language:

english

File:

PDF, 688 KB

english, 1977

44

The Possible Role of Cytochrome P-450 in the Liver “First Pass Elimination” of a P-Receptor Blocking Drug

Robert Grundin, Peter Moldéus, Sten Orrenius, Karl Olov Borg, Inger Skånberg, Christer von Bahr

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1974

Language:

english

File:

PDF, 962 KB

english, 1974

45

Dithiocarbamate Toxicity toward Thymocytes Involves Their Copper-Catalyzed Conversion to Thiuram Disulfides, Which Oxidize Glutathione in a Redox Cycle without the Release of Reactive Oxygen Species

Mark J. Burkitt, Hugh S. Bishop, Lesley Milne, Shui Ying Tsang, Gordon J. Provan, C.Stefan I. Nobel, Sten Orrenius, Andrew F.G. Slater

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 217 KB

english, 1998

46

Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes

Donato Di Monte, David Ross, Giorgio Bellomo, Lena Eklöw, Sten Orrenius

Journal:

Archives of Biochemistry and Biophysics

Year:

1984

Language:

english

File:

PDF, 822 KB

english, 1984

47

Metabolism of hydrogen peroxide in isolated hepatocytes: Relative contributions of catalase and glutathione peroxidase in decomposition of endogenously generated H2O2

Dean P. Jones, Lena Eklöw, Hjördis Thor, Sten Orrenius

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 1.00 MB

english, 1981

48

Mobilization of the hormone-sensitive calcium pool increases hepatocyte tight junctional permeability in the perfused rat liver

Juan Llopis, George E.N. Kass, Steven K. Duddy, Geoffrey C. Farell, Annie Gahm, Sten Orrenius

Journal:

Year:

1991

Language:

english

File:

PDF, 457 KB

english, 1991

49

The role of intracellular oxidants in apoptosis

Andrew F.G. Slater, C. Stefan, I. Nobel, Sten Orrenius

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

1995

Language:

english

File:

PDF, 388 KB

english, 1995

50

Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release

Mari Enoksson, Aristi Potamitou Fernandes, Stefanie Prast, Christopher Horst Lillig, Arne Holmgren, Sten Orrenius

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 330 KB

english, 2005

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